Alfaxalone is an injectable product used in dogs and cats to induce anesthesia. The animal may then be put on a gas-inhaled anesthesia machine, or may be maintained on Alfaxalone.
WHAT IS THIS DRUG?
- A steroid general anesthetic
- Alfaxalone is given by intravenous or intramuscular injection in dogs and cats
REASONS FOR PRESCRIBING:
- Alfaxalone is an induction agent used to induce anesthesia prior to inhalation anesthesia
- May also be used to maintain anesthesia
- Sedation can be achieved through low doses given intramuscularly
WHAT DOGS/CATS SHOULD NOT TAKE THIS MEDICATION?
- Safety in animals less than 12 weeks has not been evaluated
- Pets receiving other intravenous anesthetic agents
- Safety has not been established where pregnancy is to be continued, or during lactation (nursing)
- Effects upon fertility is unknown
- Pets with known hypersensitivity to Alfaxalone
Alfaxalone will be given by your veterinarian.
Fasting is advisable before receiving Alfaxalone.
One or more premedicant may be used to lessen the dose of Alfaxalone required.
Following anesthesia induction, an endotracheal tube (breathing tube) will likely be used to maintain a clear airway. Oxygen may also be administered.
To reduce the risk of low blood oxygen levels, oxygen will likely be given during induction and maintenance.
Induction is usually smooth, although some cats experience minor muscle twitching.
May be given alone as a single bolus injection, or in incremental doses. Incremental doses will not prolong recovery.
Recovery may be prolonged (but smoother) if given premedicants.
Veterinary staff will frequently monitor respiratory and cardiac function, especially in aged or stressed patients or those undergoing a caesarean section.
During recovery, the pet is best left undisturbed thereby minimizing any muscle twitching and paddling.
An analgesic (pain killer) may also be provided if the procedure is anticipated to be painful.
WHAT IF DOSE IS MISSED?
STORAGE AND WARNINGS:
Alfaxalone should be stored in the box at controlled room temperature away from heat and direct sunlight. Do not refrigerate or freeze.
This product does not contain any preservatives. Vial contents should be used within 24 hours of opening. Any remaining solution and the vial should be discarded according to national requirements.
Keep this and all medication out of reach of children and pets.
Should the product come into contact with eyes or skin, wash off immediately with water.
Call a physician immediately in case of accidental oral intake or self-injection of this product.
POTENTIAL SIDE EFFECTS:
- During recovery, the pet is best left undisturbed thereby minimizing muscle twitching and paddling
- Transient apnea (cessation of breathing) or respiratory depression may occur in dogs (dose-related). Oxygen supplementation via the endotracheal tube should be used +/- ventilation.
- Dose-related hypotension (low blood pressure) may occur at time of injection
- Contact your veterinarian immediately if you think you pet has a medical problem or side effect from this product's therapy
CAN THIS DRUG BE GIVEN WITH OTHER DRUGS?
- Yes, possible interactions may occur with other intravenous anesthetic agents or other CNS depressants
- If your pet experiences any unusual reactions post-treatment, contact your veterinarian
If an overdose is suspected, prompt therapy will be initiated.
WHAT TO TELL/ASK VETERINARIAN BEFORE GIVING MEDICATION?
Talk to your veterinarian about:
- When your pet has last eaten (vomiting may occur post injection)
- When will your pet need to be rechecked
- What tests may need to be performed prior to Alfaxalone administration
- Risks and benefits of using this drug
Tell your veterinarian about:
- If your pet has experienced side-effects on other drugs/products
- If your pet has experienced liver or kidney disease now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- All medicines and supplements that you are giving your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medicines can be given together.
- If your pet is pregnant or nursing or if you plan to breed your pet
WHAT ELSE SHOULD I KNOW?
Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.
This is just a summary of information about Alfaxalone. If you have any questions or concerns about Alfaxalone, contact your veterinarian.