This drug inhibits an enzyme resulting in a decrease in the amount of uric acid produced in the body. Allopurinol is available in tablets.
WHAT IS THIS DRUG?
- A xanthine oxidase inhibitor
- Given by mouth
REASONS FOR PRESCRIBING:
- To prevent formation of urate bladder stones
- An alternative treatment for Leishmania and Trypanosoma parasites
WHAT DOGS/CATS SHOULD NOT TAKE THIS MEDICATION?
- Animals with liver or kidney disease
- Animals that may be pregnant or nursing
- Animals with a known hypersensitivity or allergy to this drug should not take this medication
Read and follow the prescription label carefully.
Give the exact amount prescribed and only as often as directed.
Give this medication for as long as your veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.
Baseline blood work and urinalysis are recommended to assess your pet's general health before starting this drug.
Periodic blood work and follow-up urinalysis are required to monitor allopurinol's effect on the body as long-term therapy is often necessary.
Dose adjustments may be made based upon these results and an assessment of how your dog or cat is responding clinically.
Call ahead for refills.
Ideally, give medication at the same time(s) daily.
This medication is often given in conjunction with a low purine diet to avoid formation of other bladder stones.
WHAT IF A DOSE IS MISSED?
If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.
STORAGE AND WARNINGS:
Allopurinol should be stored in a childproof container in a cool, dry place at room temperature away from heat and direct sunlight.
Keep this and all medication out of reach of children and pets.
Call your physician immediately if you accidentally take this product.
POTENTIAL SIDE EFFECTS:
Chronic use of this medication without proper attention to diet can cause xanthine bladder stones and possible difficulty with urinating
This medication can affect the gastrointestinal system causing nausea, vomiting, cramping, and diarrhea
This medication can affect the liver
This medication can affect the skin causing hives, itchiness, or a rash
This medication can cause bone marrow suppression
If these symptoms persist or you notice anything else unusual, contact your veterinarian
CAN THIS DRUG BE GIVEN WITH OTHER DRUGS?
Yes, but possible interactions may occur when giving allopurinol in conjunction with: certain diets, aminophylline, ammonium chloride, amoxicillin, ampicillin, azathioprine, cyclophosphamide, furosemide, methionine, theophylline, trimethoprim/sulfas, and oral anticoagulants like warfarin
Drugs other than those listed may also interact with allopurinol
Do not give new food or medications without first talking to your veterinarian
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Contact your veterinarian immediately if your pet receives more than the prescribed amount.
WHAT TO TELL/ASK A VETERINARIAN BEFORE GIVING MEDICATION?
Talk to your veterinarian about:
- When your pet will need to be rechecked
- What tests may need to be performed prior to and during treatment with this drug
- What are the risks and benefits of using this drug
Tell your veterinarian about:
- If your pet has experienced side-effects on other drugs/products
- If your pet has experienced digestive upset now or ever
- If your pet has experienced liver or kidney disease now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medications can be given together.
- If your pet is pregnant, nursing or if you plan to breed your pet
WHAT ELSE SHOULD I KNOW?
Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.
As with all prescribed medicines, allopurinol should only be given to the pet for which it was prescribed.
It should be given only for the condition for which it was prescribed.
This is just a summary of information about allopurinol. If you have any questions or concerns about allopurinol or the condition it was prescribed for, please contact your veterinarian.