Aminopentamide hydrogen sulfate
TRADE NAMES:Centrine Injection
This drug reduces spasms in the gastrointestinal system. It also decreases the production of gastric acid and motility in the stomach. Aminopentamide is available as tablets and as an injectable.
WHAT IS THIS DRUG?
- An antispasmodic and anticholinergic agent
- Given by mouth or injection
REASONS FOR PRESCRIBING:
To prevent nausea, vomiting and diarrhea
WHAT DOGS/CATS SHOULD NOT TAKE THIS MEDICATION?
- Animals with obstructions or infections in the gastrointestinal system
- Animals with obstruction of the urinary system
- Animals with liver or kidney disease
- Animals with heart disease or high blood pressure
- Animals with hyperthyroidism, glaucoma or myasthenia gravis
- Animals that are geriatric or pediatric
- Animals that may be pregnant or nursing
- Animals with a known hypersensitivity or allergy to this drug should not take this medication
Read and follow the prescription label carefully.
Discuss with your veterinarian if this medication is to be given with food.
Give the exact amount prescribed and only as often as directed.
Give this medication for as long as your veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.
Dose adjustments may be made based upon an assessment of how your dog or cat is responding clinically.
Call ahead for refills.
Ideally, give medication at the same time(s) daily.
WHAT IF A DOSE IS MISSED?
If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.
STORAGE AND WARNINGS:
Aminopentamide should be stored in a childproof container in a cool, dry place at room temperature away from heat and direct sunlight.
Keep this and all medication out of reach of children and pets.
Call your physician immediately if you accidentally take this product.
POTENTIAL SIDE EFFECTS:
- This medication can cause dry mouth, dry eyes, and blurred vision
- This medication can cause difficulty with urination
- If these symptoms persist or you notice anything else unusual, contact your veterinarian
CAN THIS DRUG BE GIVEN WITH OTHER DRUGS?
- Yes, but possible interactions may occur when giving aminopentamide in conjunction with: acepromazine, antihistamines, long-term corticosteroid use, disopyramide, meperidine, metaclopramide, nitrofurantoin, primidone, procainamide, quinidine, sympathomimetics (phenylpropanalomine), thiazide diuretics (hydrochlorothiazide, chlorothiazide), and valium
- Drugs other than those listed may also interact with aminopentamide
- Do not give new food or medications without first talking to your veterinarian
- If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Contact your veterinarian immediately if your pet receives more than the prescribed amount.
WHAT TO TELL/ASK A VETERINARIAN BEFORE GIVING MEDICATION?
Talk to your veterinarian about:
- When your pet will need to be rechecked
- What tests may need to be performed prior to and during treatment with this drug
- What are the risks and benefits of using this drug
Tell your veterinarian about:
- If your pet has experienced side-effects on other drugs/products
- If your pet has experienced digestive upset now or ever
- If your pet has experienced liver or kidney disease now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medications can be given together.
- If your pet is pregnant, nursing or if you plan to breed your pet
WHAT ELSE SHOULD I KNOW?
Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.
As with all prescribed medicines, aminopentamide should only be given to the pet for which it was prescribed.
It should be given only for the condition for which it was prescribed.
This is just a summary of information about aminopentamide. If you have any questions or concerns about aminopentamide or the condition it was prescribed for, please contact your veterinarian.