This drug is a synthetic hormone that is used primarily in dogs and cats to help increase muscle tone of the bladder. Diethylstilbestrol is available in many forms from a compounding pharmacy.
WHAT IS THIS DRUG?
- A type of estrogen
- Given by mouth
REASONS FOR PRESCRIBING:
- To treat hormone responsive urinary incontinence in spayed dogs and cats
WHAT DOGS/CATS SHOULD NOT TAKE THIS MEDICATION?
- Animals that are not spayed
- Animals that are breeding males
- Animals with mammary cancer
- Animals with bone marrow disease
- Animals that may be pregnant or nursing
- Animals with a known hypersensitivity or allergy to this drug should not take this medication
Read and follow the prescription label carefully.
Give the exact amount prescribed and only as often as directed.
Discuss with your veterinarian if this medication is to be given with food.
Give this medication for as long as your veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.
Baseline blood work and urinalysis may be recommended to assess your pet's general health before starting this drug.
Periodic blood work and urinalysis to monitor diethylstilbestrol's effect on the body is also advised as long-term therapy is often necessary.
Dose adjustments may be made based upon these results and an assessment of how your dog or cat is responding clinically.
Call ahead for refills.
Ideally, give this medication at the same time(s) daily.
WHAT IF A DOSE IS MISSED?
If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.
STORAGE AND WARNINGS:
Diethylstilbestrol should be stored in a childproof container in a cool, dry place at room temperature away from heat and direct sunlight.
Keep this and all medication out of reach of children and pets.
Diethylstilbestrol can cause abortions and should not be handled by pregnant women or women trying to become pregnant.
Call your physician immediately if you accidentally take this product.
POTENTIAL SIDE EFFECTS:
- This medication can affect the gastrointestinal system causing lack of appetite, vomiting and diarrhea
- This medication can affect the reproductive system in unspayed females causing uterine infections
- This medication can cause lethargy, an increase in thirst and urination
- This medication can affect the bone marrow resulting in abnormal bruising, bleeding, and an increase risk for infections
- If these symptoms persist or you notice anything else unusual, contact your veterinarian
CAN THIS DRUG BE GIVEN WITH OTHER DRUGS?
- Yes, but possible interactions may occur when giving diethylstilbestrol in conjunction with: corticosteroids, phenobarbital, rifampin, warfarin
- Drugs other than those listed may also interact with diethylstilbestrol
- Do not give new food or medications without first talking to your veterinarian
- If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Contact your veterinarian immediately if your pet receives more than the prescribed amount.
WHAT TO TELL/ASK A VETERINARIAN BEFORE GIVING MEDICATION?
Talk to your veterinarian about:
- When your pet will need to be rechecked
- What tests may need to be performed prior to and during treatment with this drug
- What are the risks and benefits of using this drug
Tell your veterinarian about:
- If your pet has experienced side-effects on other drugs/products
- If your pet has experienced digestive upset now or ever
- If your pet has experienced liver or kidney disease now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medications can be given together.
- If your pet is pregnant, nursing or if you plan to breed your pet
WHAT ELSE SHOULD I KNOW?
Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.
As with all prescribed medicines, diethylstilbestrol should only be given to the pet for which it was prescribed.
It should be given only for the condition for which it was prescribed.
This is just a summary of information about diethylstilbestrol. If you have any questions or concerns about diethylstilbestrol or the condition it was prescribed for, please contact your veterinarian.