Equine Ceftiofur (Rx)
Excede Sterile Suspension for Horses
This drug is an antibiotic that fights bacterial infections. Ceftiofur sodium is available as an injectable solution.
WHAT IS THIS DRUG?
- A broad spectrum cephalosprin antibiotic
- Given by intramuscular (IM) injection
REASONS FOR PRESCRIBING:
- Used to treat susceptible bacterial infections.
- Commonly used for the treatment of respiratory infections in horses
Ceftiofur should be given according to your veterinarian’s instructions. Read and follow the prescription label and route of administration carefully.
Give the exact amount prescribed and only as often as directed.
Give this medication for as long as your veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.
Baseline blood work may be recommended to assess your horse’s general health before starting this medication.
Dose adjustments may be made based upon an assessment of how your horse is responding clinically.
Ideally, give this medication at the same time(s) daily.
Ceftiofur sodium is purchased as a powder and should be reconstituted as follows:
1 gram vial - Reconstitute with 20 mL sterile water for injection. Each mL of the resulting solution contains ceftiofur sodium equivalent to 50 mg ceftiofur.
4 gram vial - Reconstitute with 80 mL sterile water for injection. Each mL of the resulting solution contains ceftiofur sodium equivalent to 50 mg ceftiofur.
Shake thoroughly prior to use.
Common areas for intramuscular (IM) injections include the base of the neck and the hamstrings as they are both large muscles. The base of the neck provides a relatively safe location for the handler and is located in a triangle formed by the crest, the neck vertebrae, and the point of the shoulder. The hamstring locations should only be used by experienced handlers as there are increased safety risks. The top of the rump is not a recommended site because abscesses in this location are difficult to treat.
If you are unsure how your horse will react to an injection, request assistance or demonstration by your veterinarian.
WHAT IF A DOSE IS MISSED?
If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.
STORAGE AND WARNINGS:
Ceftiofur should be stored in a childproof container in a cool, dry place at room temperature away from heat and direct sunlight. Once reconstituted, Ceftiofur should be used within 12 hours at room temperature or stored in the refrigerator for up to 7 days. At the end of this period, any remaining reconstituted product can be frozen once for up to 8 weeks. When required, the frozen product can be thawed either at room temperature or warmed under running water. Discard any unused product immediately after being thawed.
Keep this and all medication out of reach of children and pets.
Individuals with a known sensitivity to penicillin or cephalosporins should avoid contact with this medication.
Avoid direct contact with skin, eyes, mouth, and clothing.
Call your physician immediately if you accidentally take this product or if an allergic reaction occurs.
POTENTIAL SIDE EFFECTS:
- This medication may cause a transient decrease in food consumption
- There is a risk for antibiotic associated diarrhea or colic
- There is a risk for injection site discomfort with intramuscular (IM) injections
- High doses have been reported to cause altered bacterial flora resulting in large intestinal inflammation, abnormal stool, reduced appetite, weight loss, and inactivity
- All antibiotics have the potential to cause an over-growth of non-susceptible organisms
- All injectable medications have the potential to cause an immediate allergic or anaphylactic reaction. Affected animals may have a swelling, hives, changes in respiration, and display signs of agitation. This can be a severe and life threatening reaction, immediate treatment with epinephrine is often required.
- Notify your veterinarian immediately if your horse experiences any adverse reactions to this medication
CAN THIS DRUG BE GIVEN WITH OTHER DRUGS?
- Avoid concurrent use of aminoglycosides and other potentially kidney toxic drugs
- Drugs other than those listed may also interact with Ceftiofur
- Do not give new food or medications without first talking to your veterinarian
- If your horse experiences any unusual reactions when taking multiple medications, contact your veterinarian
Contact your veterinarian immediately if your horse receives more than the prescribed amount.
WHAT ELSE SHOULD I KNOW?
Notify your veterinarian if your horse’s condition does not improve or worsens despite this treatment.
This product should not be used in horses intended for human consumption.
Check with the appropriate regulatory body regarding the use in competition horses.
As with all prescribed medication, Ceftiofur should only be given to the horse for which it was prescribed.
It should be given only for the condition for which it was prescribed.
This is just a summary of information about Ceftiofur. If you have any questions or concerns about this product or for the condition it was prescribed, please contact your veterinarian.