Fentanyl transdermal patch (CII)
The Fentanyl transdermal patch is used in dogs and cats to provide prolonged relief from acute pain following trauma or surgery. This opioid drug may also be used for chronic pain management in conditions such as cancer. Pain relief usually occurs within 12-24 hours of application and is effective for 3-5 days. The convenient patch avoids the repeated patient handling needed for administration of oral and injectable drugs.
WHAT IS THIS DRUG?
- Fentanyl patch is an opioid analgesic (pain killer), schedule II drug (requiring a DEA controlled drug license)
- The topical patch releases drug into the blood across the skin
- Effective blood levels are generally maintained for approximately 72 hours
- May be used alone or in combination with other drugs
- Veterinary staff will apply the Fentanyl transdermal patch to a shaved area
- Four different patch sizes are available, and chosen based upon body weight
REASONS FOR PRESCRIBING:
- The Fentanyl transdermal patch is a useful ‘hands off’ method of delivering pain medication
- Ideal for managing pain following trauma or surgery
The Fentanyl transdermal patch is applied to a shaved area by your veterinary staff in order to ensure proper application.
The patch should not be applied to a part of the body on which the animal may lie. The increased pressure and heat from lying down may cause extra drug absorption.
Common application sites are at the back of the neck, by the top of the tail or on the side of the chest. The area is clipped but not cleaned with any products. The protective backing is peeled off the patch and the sticky backing is then placed firmly against the pet’s skin and held in place with light pressure for one minute. If the edges do not adhere well then glue may be applied or a light bandage placed over the patch.
There are different strengths of patches and their selection is based upon the pet’s body weight. If it is necessary to use a half patch, the patch should not be cut, but the gel membrane should be covered by tape.
Pain relief usually occurs within 6 (cats) -12 (dogs) hours of application, although there can be significant variation in effectiveness between patients.
For elective surgeries (eg. spay, declaw), the patch is usually placed 12-20 hours pre-surgery.
If the animal is already in pain prior to application of the patch, other pain killers will be used for the first 12-20 hours.
Drug levels rapidly decline after patch removal.
Do not place collars or harnesses over the patch.
*Because this drug is a schedule II drug, after use the patch must be disposed of according to DEA regulations. In most cases, veterinarians will request that you bring your pet back to the veterinary clinic for patch removal and proper disposal.
WHAT IF A DOSE IS MISSED?
If your pet needs repeated dosing with this product, do your best to ensure that a dose is not missed. Continuous delivery of pain relief is more effective than periodic administration of pain relief. Return to your veterinary clinic for patch replacement as scheduled by your veterinarian.
STORAGE AND WARNINGS:
Store patches in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.
The patch may be toxic if swallowed.
Patches should be applied immediately after their sealed package has been opened.
Keep this and all medication out of reach of children and pets. Children can suffer serious adverse effects, including death, if they apply the pet’s patch to their own skin. Ensure that children and other pets do not have access to your pet’s Fentanyl transdermal patch.
Contact a doctor immediately if a child comes in contact with a patch.
POTENTIAL SIDE EFFECTS:
- Respiratory depression, slow heartbeat. Slowed breathing will not allow the dog to cool themselves effectively thereby increasing their risk for heat exhaustion or heat stroke.
- Patients with a fever may absorb more drug than they should and suffer adverse effects. If the patch is exposed to heat, there is a significant risk of increased absorption as well. Do not use a heating pad, electric blankets, sit on a heating vent or allow the pet to sleep on a water bed.
- Possible rash at application site
- Sedation may be observed in dogs
- Loss of appetite, constipation, salivation, panting and difficulty urinating
- Possible initial restlessness or agitation. This can be alleviated by a tranquillizer if necessary.
- Allergy symptoms to this medication include: scratching, facial swelling, hives, sudden diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma
- It is important to contact your veterinarian immediately if you think you pet has a medical problem or side effect from this product's therapy
CAN THIS DRUG BE GIVEN WITH OTHER DRUGS?
- Yes, but possible interactions may occur with anesthetics, antihistamines, cimetidine, opioid analgesics, seizure medications and tranquilizers
- Do not use Fentanyl transdermal patch for 14 days after using amitraz (used in some flea collars and Mitaban), MAOIs (eg. Anipryl, L-Deprenyl) or isoniazid
- If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Contact your veterinarian immediately if your pet is breathing too slowly, is vomiting, constipated, depressed or unusually excited.
WHAT DOGS/CATS SHOULD NOT RECEIVE THIS MEDICATION?
- Pets with heart, lung, liver or kidney disease
- Use with caution in older, very ill or debilitated pets
- Breeding, pregnant or nursing animals
- Pets with known hypersensitivity to opioid drugs
WHAT TO TELL/ASK VETERINARIAN BEFORE GIVING MEDICATION?
Talk to your veterinarian about:
- When will your pet need to be rechecked
- What tests may need to be performed prior to and during treatment with this drug
- Risks and benefits of using this drug
Tell your veterinarian about:
- If your pet has experienced side-effects on other drugs/products
- If your pet has experienced digestive upset now or ever
- If your pet has experienced liver or kidney disease now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medicines can be given together.
- If your pet is pregnant or nursing or if you plan to breed your pet
WHAT ELSE SHOULD I KNOW?
Notify your veterinarian if your animal is still painful despite this treatment.
As with all prescribed medicines, Fentanyl transdermal patch should only be used on the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.
This is just a summary of information about the Fentanyl transdermal patch. If you have any questions or concerns about the Fentanyl transdermal patch or for the condition it was prescribed, contact your veterinarian.