Gentamicin sulfate + Betamethasone valerate otic (Rx)

TRADE NAMES:

GenOne Otic Solution

GENERAL DESCRIPTION:

This ear medication contains an antibacterial and an anti-inflammatory agent. It is useful for treating acute or chronic canine otitis externa (outer ear infections) and superficial skin lesions in dogs and cats when caused by bacteria susceptible to gentamicin. The easy-to-use squeeze bottle is available in 7.5 mL and 15 mL sizes.

WHAT IS THIS DRUG?

• A combination of an aminoglycoside antibiotic (gentamicin sulfate) and an adrenocorticoid (betamethasone valerate)
• For topical use on skin (dogs and cats) and in ears (dogs)

REASONS FOR PRESCRIBING:

• For the treatment of dogs with acute or chronic otitis externa associated with bacteria sensitive to gentamicin
• To reduce the discomfort, redness, swelling, crusty material and odor associated with ear inflammations and infections
• To treat skin lesions infected with bacteria susceptible to gentamicin

WHAT PETS SHOULD NOT USE THIS MEDICATION?

• Pets with a ruptured ear drum
• Do not use this product if your pet is pregnant
• If your pet has had an allergic reaction to any of the ingredients or to similar products

Read and follow the label carefully.
Therapy length will depend upon the severity of the pet’s condition, and how quickly they respond. Follow your veterinarian’s directions to ensure that you do not discontinue therapy prematurely.
Ear Infections:
Your veterinarian will need to examine the ears to ensure that the ear drum(s) is/are intact.
Your veterinarian may want to perform a culture evaluation of the ear prior to starting this medication.
The external ear should be thoroughly cleaned and dried before treatment. Excessive hair should be trimmed from the treatment area. Have your veterinarian or veterinary technician show you how to properly clean your dog's ears and apply this product.
Instill 3-8 drops room temperature solution into external ear canal twice daily for 7-14 days, or as directed by your veterinarian .
Massage the external ear canal carefully to ensure adequate medication distribution.
Superficial infected skin lesions: Clean lesion and adjoining area before treatment. Remove any excessive hair as necessary. Apply enough solution to cover the treatment area twice daily for 7-14 days, or as directed by your veterinarian.

WHAT IF A DOSE IS MISSED?

If a treatment is missed, perform it as soon as you can. If it is time already for the next treatment, skip the missed treatment and go back to the normal schedule.

STORAGE AND WARNINGS:

Store between 2° and 25°C (36° and 77°F).
Do not allow your pet to ingest this product. Avoid getting it in your pet's eyes.
Keep this and all medication out of reach of children and pets.
Call your physician immediately if you accidentally take this product.

POTENTIAL SIDE EFFECTS:

• If hearing loss, head tilt or dizziness are noted, discontinue use of this product immediately and contact your veterinarian.
• All aminoglycosides have the potential to produce reversible and irreversible vestibular, cochlear and renal toxicity. Gentamicin can also cause birth defects during the first phase of pregnancy.
• Cushing's syndrome, delayed wound healing and immunosuppression have been reported in patients with prolonged or repeated steroid therapy.
• If ingested, side effects of corticosteroids include: increased thirst and urination, increased appetite and weight gain, panting, diarrhea, vomiting and behavior changes.
• Gentamicin can cause premature birth in pregnant animals. Corticosteroids can cause birth defects during the first phase of pregnancy. Avoid ingestion.

CAN THIS DRUG BE GIVEN WITH OTHER DRUGS?

• Yes, but do not give or use other corticosteroids or aminogylcoside antibiotics during treatment with this medication unless prescribed by your veterinarian.
• If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.

OVERDOSING?

Early signs of overdose or toxicity include loss of hearing or balance or vomiting. If you see these signs, know or suspect an overdose, contact your veterinarian immediately.

What else should I know?
  Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.

As with all prescribed medicines, Gentamicin sulfate + Betamethasone valerate otic should only be used on the pet for which it was prescribed.

It should also only be used for the condition for which it was prescribed.

WHAT TO TELL/ASK A VETERINARIAN BEFORE GIVING MEDICATION?

Talk to your veterinarian about:

• When will your pet need to be rechecked
• What tests may need to be performed prior to and during treatment with this drug
• What are the risks and benefits of using this drug

Tell your veterinarian about:

• If your pet has experienced side-effects on other drugs/products
• If your pet has any hearing loss
• If your pet has experienced any other medical problems or allergies now or ever
• All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medicines can be given together.
• If your pet is pregnant, nursing or if you plan to breed your pet