This is a behavior modifying medication. Behavior issues in dogs and cats are a common problem that are challenging for many owners. Some behavior disorders are simply frustrating while others can be unacceptable or potentially dangerous. Often, medications are utilized to assist with training and behavior modification is encouraged. Imipramine is available in the form of tablets and capsules.
WHAT IS THIS DRUG?
- A tricyclic antidepressant which increases the levels of serotonin in the brain
- Given by mouth
REASONS FOR PRESCRIBING
- Used to assist with modifying or managing unwanted behaviors such as urinary incontinence and separation anxiety
- May be used as an adjunct for the management of chronic pain
Read and follow the prescription label carefully.
Give the exact amount prescribed and only as often as directed.
It may require several days or weeks to determine efficacy of this medication.
Discuss with your veterinarian if this medication is to be given with food. If this medication causes upset on an empty stomach, offer with a small amount of food or treats.
Give this medication for as long as your veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.
Baseline blood work may be recommended to assess your pet's general health before starting this medication.
Periodic blood work to monitor its effects on the body may also be advised if long term therapy is necessary. Dose adjustments may be made based upon these results and an assessment of how your dog or cat is responding clinically.
Ensure your pet has plenty of fresh, clean drinking water while taking this medication.
Call ahead for refills.
Ideally, give this medication at the same time(s) daily.
WHAT IF A DOSE IS MISSED?
If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.
STORAGE AND WARNINGS:
Imipramine should be stored in a childproof container in a cool, dry place at room temperature away from heat and direct sunlight.
Do not give your pet aged cheese products as they can interact with this medication
Keep this and all medication out of reach of children and pets.
Call your physician immediately if you accidentally take this product.
POTENTIAL SIDE EFFECTS
- This medication can affect the heart causing an increase in heart rate
- This medication can affect the central nervous system causing sedation, hyperexcitability, tremors, and seizures
- This medication can cause a dry mouth, urine retention, and constipation
- This medication can cause bone marrow suppression resulting in anemia, abnormal bleeding and potential immune suppression
- If you notice any of these symptoms or if your pet's condition worsens contact your veterinarian
CAN THIS DRUG BE GIVEN WITH OTHER DRUGS?
- Yes, but possible interactions may occur when giving in conjunction with: anticholinergic agents, cimetidine, cisapride, clonidine, central nervous system depressants, levodopa, meperidine, pentazocine, phenobarbital, quinidine, rifampin, selective serotonin reuptake inhibitors, sympathomimetics agents, monoamine oxidase inhibitors (flea collars and Anipryl), and thyroid agents
- Drugs other than those listed may also interact with Imipramine
- Do not give new food or medications without first talking to your veterinarian
- If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
This medication can be toxic if overdosed. Life threatening changes to heart rhythm and cardiorespiratory collapse can occur. Contact your veterinarian immediately if your pet receives more than the prescribed amount.
WHAT DOGS/CATS SHOULD NOT TAKE THIS MEDICATION?
- Use with caution in animals with epilepsy or a history of seizures
- Use with caution in animals with known liver disease
- Animals that may be pregnant or nursing
- Animals with a known hypersensitivity or allergy to this drug should not take this medication
WHAT TO TELL/ASK A VETERINARIAN BEFORE GIVING MEDICATION?
- When your pet will need to be rechecked
- What tests may need to be performed prior to and during treatment with this drug
- What are the risks and benefits of using this drug
- If your pet has experienced side effects on other drugs/products
- If your pet has experienced digestive upset now or ever
- If your pet has experienced liver or kidney disease now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medications can be given together.
- If your pet is pregnant, nursing or if you plan to breed your pet
WHAT ELSE SHOULD I KNOW?
Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.
As with all prescribed medicines, Imipramine should only be given to the pet for which it was prescribed.
It should be given only for the condition for which it was prescribed.
This is just a summary of information about Imipramine. If you have any questions or concerns about this medication or the condition it was prescribed for, please contact your veterinarian.