Medroxyprogesterone is a synthetic hormone. This medication is available as a tablet and an injectable solution.
WHAT IS THIS DRUG?
- A synthetic form of the hormone progesterone
- Given by mouth or as an injection under the skin (subcutaneous)
REASONS FOR PRESCRIBING:
- To manage unwanted sexual-based behaviors such as roaming, aggression, urine marking, and mounting
- To manage feline behavior-related skin conditions, e.g. feline psychogenic alopecia and dermatitis
- To treat certain prostate conditions
- For long-term female reproductive control
WHAT DOGS/CATS SHOULD NOT TAKE THIS MEDICATION?
- There are often safer alternatives that should be considered due to the serious side effects of this medication
- This medication should not be used in sexually immature pets
- This medication should not be used in pets that are currently pregnant or having a false pregnancy (pseudopregnancy)
- This medication should not be used in female pets that are in diestrus or during prolonged heat cycles
- The medication should not be used in female pets that have uterine hemorrhage or a potential uterine infection
- This medication should not be used in pets with diabetes mellitus
- Safety in nursing pets has not been established
- Animals with a known hypersensitivity or allergy to this drug should not take this medication
Read and follow the label carefully.
Give the exact amount prescribed and only as often as directed.
Give this medication for as long as your veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.
Baseline blood work may be recommended to assess your pet's general health before starting this medication.
Dose adjustments may be made based upon an assessment of how your dog or cat is responding clinically.
Call ahead for refills.
Ideally, give the medication at the same time(s) daily.
WHAT IF A DOSE IS MISSED?
If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.
STORAGE AND WARNINGS:
Medroxyprogesterone should be stored in a childproof container in a cool, dry place at room temperature away from heat and direct sunlight.
Keep this and all medication out of reach of children and pets.
Call your physician immediately if you accidentally take this product.
POTENTIAL SIDE EFFECTS:
- There are often safer alternative treatments that should be considered due to the serious side effects of this medication
- This medication can cause an increase in thirst, appetite, and weight gain
- This medication can cause personality changes, depression, and lethargy
- This medication can affect the adrenal glands and the ability of your pet to handle stressful situations
- This medication can affect the mammary glands leading to enlargement, milk production or lactation, and potential mammary cancer
- This medication can cause diabetes mellitus and hypothyroidism
- This medication can cause a uterine infection (pyometra)
- This medication can inhibit male libido and fertility
- Injections under the skin (subcutaneous) can lead to local hair loss and changes in skin pigmentation
- If you notice any of these symptoms or if your pet's condition worsens contact your veterinarian
CAN THIS DRUG BE GIVEN WITH OTHER DRUGS?
- Yes, but possible interactions may occur with corticosteroids, felbamate and rifampin
- Drugs other than those listed may also interact with Medroxyprogesterone
- Do not give new food or medications without first talking to your veterinarian
- If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Contact your veterinarian immediately if pet receives more than the prescribed amount.
WHAT TO TELL/ASK A VETERINARIAN BEFORE GIVING MEDICATION?Talk to your veterinarian about:
- Appropriate training and behavior modification techniques
- When your pet will need to be rechecked
- What tests may need to be performed prior to and during treatment with this drug
- What are the risks and benefits of using this drug
- If your pet has experienced side effects on other drugs/products
- If your pet has experienced digestive upset now or ever
- If your pet has experienced liver or kidney disease now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medications can be given together.
- If your pet is pregnant, nursing or if you plan to breed your pet
WHAT ELSE SHOULD I KNOW?
Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.
As with all prescribed medicines, Medroxyprogesterone should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.
This is just a summary of information about Medroxyprogesterone. If you have any questions or concerns about this medication or for the condition it was prescribed, contact your veterinarian.