Effective Treatment of Vomiting in Dogs

Dog vomiting

Vomiting is not fun for anybody – including your dog. The good news is that there is an FDA-approved veterinary medication developed specifically for dogs that can help treat and prevent this common clinical sign.


CERENIA (maropitant citrate) is the first and only FDA-approved medication to treat and prevent acute vomiting in dogs, including preventing vomiting due to motion sickness. CERENIA was developed just for dogs. It is a non-drowsy medication that comes in two formulations – an injection given by your veterinarian or tablets that can be given within the hospital or at home. And it only needs to be given once a day!

How Does CERENIA Work?

Dogs vomit for a variety of reasons – eating garbage, motion sickness, anxiety, or various medical conditions such as kidney or liver disease. When this happens, vomiting signals are sent to the part of the brain called the “emetic center”. These signals travel through either the “central pathway,” a direct connection from the higher brain to the emetic center, or the “peripheral pathway,” a direct or an indirect connection from the gut, bloodstream, or balance center (called the “vestibular apparatus” – which triggers motion sickness). The “chemoreceptor trigger zone” or CRTZ is a part of the brain that detects signals from the vestibular apparatus or from the indirect peripheral pathway and translates the signals to the emetic center.

When the signal reaches the emetic center via one or a combination of these pathways, dogs vomit. CERENIA blocks these signals to vomit regardless of the pathway. Therefore, vomiting is prevented. CERENIA is the only FDA-approved medication that blocks both direct and indirect signals sent to the emetic center, which makes it effective at treating and preventing vomiting from many different causes.

Since its launch in 2007, CERENIA has been given to many dogs and is the number one prescribed anti-vomiting medication among veterinarians1. Both veterinarians and dog owners alike have reported positive experiences with CERENIA. You can be assured that your dog is being given a safe and effective medication!

Want to learn more about how CERENIA can help if your dog vomits from motion sickness? Visit www.cerenia.com.

IMPORTANT SAFETY INFORMATION The safe use of CERENIA has not been tested in female dogs that are breeding, pregnant or are nursing, dogs that have swallowed foreign objects, and dogs that have eaten poisonous substances. Caution should be used in giving CERENIA to dogs with liver problems. CERENIA is recommended for dogs 16 weeks and older. The most common side effects seen with CERENIA are excessive drooling (5-13%), lethargy (9%) and vomiting not due to motion sickness (5-9%). For more information, read the full prescribing information or visit www.CERENIA.com.

1GMR Purchased, Dispensed, and Inventory Report for US Cerenia, 4Q 2010

CER0811015 © 2011 Pfizer Inc. All rights reserved. August 2011