2001-Tue Mar 19 21:29:59 EDT 2019
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By the time your regular veterinarian sends you and your favorite fur person to a cancer specialist like me, you are so distraught that anything I say is likely to make you simply “tear up and tune out.” Because I know and understand how hard it can be to have a pet with cancer, I try to focus our conversations on your questions and the most important facts of your pet’s cancer. Sometimes, I accidently let an oncology word or two slip into my conversation. I don’t mean to do this, but these are the scientific words we pet cancer specialists use every day to communicate with each other.In case your pet oncologist is like me and accidentally uses these words, I have made an “onco-speak” translation guide below.
Sarcoma/carcinoma/round cell tumor: Oncologists group tumors into three main “families”: sarcoma, carcinoma and round cell tumors.This is based on how the tumor cells appear when we look at them under the microscope. Sarcoma cells appear elongated or spindle-like, carcinoma cells form clusters, groups or sheets, and round cells are… well, round.Most times a tumor has a specific name such as a thyroid carcinoma. Other times, the tumor cells are so abnormal we can only say it comes from one of the three families and need to perform additional testing to determine its origin. Knowing the origin helps us to treat it appropriately.
Median survival time: I know that what you most want to know is how long your pet will live, but I can only give you information based on large groups of pets with similar tumors and treatments.“Median” is a statistical term used in scientific publications to communicate how long pets with a certain tumor live when treated with a particular protocol. Median represents the midpoint of the data.So, if I say the median survival time for pets with cancer X is 12 months, I don’t mean your pet will die exactly 12 months from now. What I mean is that 50 percent of pets with this type of cancer will live more than 12 months while, sadly, 50 percent will live less than that amount of time. It can be hard for me to project what an individual pet’s survival time is likely to be.
Prognostic factors: According to my dictionary, prognostic mean predicting the future or forecasting.Like the weatherman, oncologists are pretty good at anticipating what the likely outcome for your pet will be, but sometimes the tumor does not follow the rules and we can be way off base. A “prognostic factor” is something about your pet’s tumor which positively or negatively influences how well your pet will respond to treatment. Read the next two definitions, grade and stage, to understand two common prognostic factors.
Grade: If your pet has cancer, he or she will have a specialist, called a veterinary pathologist, involved in their diagnosis and care. You may never meet this specialist, but veterinary oncologists like me depend on pathologists to look at tumor biopsies under the microscope and to determine the type of tumor. For many tumors, they also “grade” the specimen.Grade is commonly determined by the number of dividing tumor cells seen in the biopsy, the degree of abnormal structures the cancer cells show, and if the tumor cells demonstrate invasion into blood vessels or underlying body structures. A higher grade typically confers a worse prognosis and spurs your pet’s oncologist to recommend more treatment. For example, a grade I mast cell tumor is typically cured by surgery alone, but a grade III tumor may need chemotherapy and radiation treatment.
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